Kinetically controlled self-assembly of DNA oligomers.
Metastable two-stranded DNA loops can be assembled into extended DNA oligomers by kinetically controlled self-assembly. Along the designed reaction pathway, the sequence of hybridization reactions is controlled by progressively revealing toeholds required to initiate strand-displacement reactions. T...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2009
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| _version_ | 1797103687766638592 |
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| author | Lubrich, D Green, S Turberfield, A |
| author_facet | Lubrich, D Green, S Turberfield, A |
| author_sort | Lubrich, D |
| collection | OXFORD |
| description | Metastable two-stranded DNA loops can be assembled into extended DNA oligomers by kinetically controlled self-assembly. Along the designed reaction pathway, the sequence of hybridization reactions is controlled by progressively revealing toeholds required to initiate strand-displacement reactions. The product length depends inversely on seed concentration and ranges from a few hundred to several thousand base-pairs. |
| first_indexed | 2024-03-07T06:23:39Z |
| format | Journal article |
| id | oxford-uuid:f384a9ed-f936-46e6-b5cb-d0da5a8e6c14 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:23:39Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:f384a9ed-f936-46e6-b5cb-d0da5a8e6c142022-03-27T12:12:50ZKinetically controlled self-assembly of DNA oligomers.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f384a9ed-f936-46e6-b5cb-d0da5a8e6c14EnglishSymplectic Elements at Oxford2009Lubrich, DGreen, STurberfield, AMetastable two-stranded DNA loops can be assembled into extended DNA oligomers by kinetically controlled self-assembly. Along the designed reaction pathway, the sequence of hybridization reactions is controlled by progressively revealing toeholds required to initiate strand-displacement reactions. The product length depends inversely on seed concentration and ranges from a few hundred to several thousand base-pairs. |
| spellingShingle | Lubrich, D Green, S Turberfield, A Kinetically controlled self-assembly of DNA oligomers. |
| title | Kinetically controlled self-assembly of DNA oligomers. |
| title_full | Kinetically controlled self-assembly of DNA oligomers. |
| title_fullStr | Kinetically controlled self-assembly of DNA oligomers. |
| title_full_unstemmed | Kinetically controlled self-assembly of DNA oligomers. |
| title_short | Kinetically controlled self-assembly of DNA oligomers. |
| title_sort | kinetically controlled self assembly of dna oligomers |
| work_keys_str_mv | AT lubrichd kineticallycontrolledselfassemblyofdnaoligomers AT greens kineticallycontrolledselfassemblyofdnaoligomers AT turberfielda kineticallycontrolledselfassemblyofdnaoligomers |