Genetic insights into the hypoxia-inducible factor (HIF) pathway.

The HIF system probably operates in all cells, in all metazoan organisms. The effects of genetic alterations in the main components of the pathway offer a very powerful way to delineate its function in normal biology and disease. With time it is likely that more subtle variations will be identified...

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Détails bibliographiques
Auteurs principaux: Kiriakidis, S, Esteban, M, Maxwell, P
Format: Journal article
Langue:English
Publié: 2007

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