Genetic insights into the hypoxia-inducible factor (HIF) pathway.
The HIF system probably operates in all cells, in all metazoan organisms. The effects of genetic alterations in the main components of the pathway offer a very powerful way to delineate its function in normal biology and disease. With time it is likely that more subtle variations will be identified...
Autori principali: | Kiriakidis, S, Esteban, M, Maxwell, P |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2007
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