Genetic insights into the hypoxia-inducible factor (HIF) pathway.

Genetic insights into the hypoxia-inducible factor (HIF) pathway.

The HIF system probably operates in all cells, in all metazoan organisms. The effects of genetic alterations in the main components of the pathway offer a very powerful way to delineate its function in normal biology and disease. With time it is likely that more subtle variations will be identified...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Kiriakidis, S, Esteban, M, Maxwell, P
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2007

Những quyển sách tương tự

Activation of hypoxia-inducible factor (HIF) pathway in varicose veins
Bằng: Lim, C, et al.
Được phát hành: (2011)

Targeting the hypoxia-inducible factor (HIF) pathway in cancer.
Bằng: Poon, E, et al.
Được phát hành: (2009)

Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis.
Bằng: Muz, B, et al.
Được phát hành: (2009)

Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
Bằng: Webb, J, et al.
Được phát hành: (2009)

Functional variation in the hypoxia-inducible factor (HIF) pathway in humans
Bằng: Petousi, N
Được phát hành: (2012)

THE HYPOXIA INDUCIBLE FACTOR (HIF) PATHWAY IN AML: THERAPEUTIC TARGETING
Bằng: Büşra Tuğçe Akman
Được phát hành: (2024-12-01)

Pathways of Hypoxia-Inducible Factor (HIF) in the Orchestration of Uterine Fibroids Development
Bằng: Maria Fedotova, et al.
Được phát hành: (2023-08-01)

Hypoxia-inducible factor pathway and diseases of the vascular wall
Bằng: Lim, C, et al.
Được phát hành: (2013)

Hypoxia-inducible factor pathway and diseases of the vascular wall.
Bằng: Lim, C, et al.
Được phát hành: (2013)

The Hypoxia-Inducible Factor (HIF) pathway in adipocytes: The role of HIF-2 in adipose inflammation and hypertrophic cardiomyopathy
Bằng: Zhong eYun, et al.
Được phát hành: (2015-03-01)

Increased activation of the hypoxia-inducible factor pathway in varicose veins
Bằng: Lim, C, et al.
Được phát hành: (2012)

Increased activation of the hypoxia-inducible factor pathway in varicose veins.
Bằng: Lim, C, et al.
Được phát hành: (2012)

Hypoxia and HIF pathway in cancer and the placenta
Bằng: Macklin, P, et al.
Được phát hành: (2017)

Inhibition of hypoxia inducible factor (HIF) hydroxylases
Bằng: Conejo-Garcia, A, et al.
Được phát hành: (2005)

Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis.
Bằng: Khan, M, et al.
Được phát hành: (2011)

Inhibition studies on hypoxia-inducible factor (HIF) hydroxylases
Bằng: Chan, M
Được phát hành: (2014)

Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2α gain-of-function mutation.
Bằng: Formenti, F, et al.
Được phát hành: (2011)

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression.
Bằng: Wood, S, et al.
Được phát hành: (1998)

The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.
Bằng: Talks, K, et al.
Được phát hành: (2000)

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.
Bằng: Raval, R, et al.
Được phát hành: (2005)

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.
Bằng: Mole, D, et al.
Được phát hành: (2009)

Kinetic investigations of the oxygen entry pathway of the hypoxia-inducible factor (HIF) prolyl hydroxylase 2
Bằng: Kearney, L
Được phát hành: (2015)

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Bằng: Stolze, I, et al.
Được phát hành: (2004)

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.
Bằng: Sowter, H, et al.
Được phát hành: (2003)

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha.
Bằng: Elkins, J, et al.
Được phát hành: (2003)

Studies on the inhibition of human hypoxia inducible factor (HIF) hydroxylases
Bằng: Yeoh, KK
Được phát hành: (2012)

Regulation of the Hypoxia-Inducible Factor (HIF) by Pro-Inflammatory Cytokines
Bằng: Mykyta I. Malkov, et al.
Được phát hành: (2021-09-01)

Hypoxia inducible factor (HIF) activity reporter cell line
Bằng: Shafee, Norazizah, et al.
Được phát hành: (2012)

Induction of KSHV latency-associated nuclear antigen (LANA) by hypoxia and hypoxia-inducible factors (HIF)
Bằng: Veeranna Ravindra P, et al.
Được phát hành: (2012-04-01)

Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
Bằng: Moritz J. Strowitzki, et al.
Được phát hành: (2019-04-01)

Targeting Hypoxia-Inducible Factor-1 (HIF-1) in Cancer: Emerging Therapeutic Strategies and Pathway Regulation
Bằng: Reem A. Qannita, et al.
Được phát hành: (2024-02-01)

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
Bằng: Hewitson, K, et al.
Được phát hành: (2002)

A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)
Bằng: Fatemeh Choopani, et al.
Được phát hành: (2019-06-01)

Mutation analysis of hypoxia-inducible factors HIF1A and HIF2A in renal cell carcinoma.
Bằng: Morris, MR, et al.
Được phát hành: (2009)

Expression of angiogenic factors and hypoxia inducible factors HIF 1, HIF 2 and CA IX in non-Hodgkin's lymphoma.
Bằng: Stewart, M, et al.
Được phát hành: (2002)

Hypoxia, hypoxia-inducible factor (HIF) and bone homeostasis: focus on osteoclast-mediated bone resorption
Bằng: Knowles, H
Được phát hành: (2015)

Role of hypoxia-inducible factor-1 (HIF-1) is angiogenesis and tumour biology
Bằng: Ratcliffe, P
Được phát hành: (1999)

Activation of the HIF pathway in cancer.
Bằng: Maxwell, P, et al.
Được phát hành: (2001)

Hypoxia-Inducible Factor-1 (Hif-1) in Experimental Brain Ischemia
Bằng: Rainald Schmidt-Kastner, et al.
Được phát hành: (2002-01-01)

The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans.
Bằng: Yi Zhang, et al.
Được phát hành: (2009-07-01)