Impact of pre-adapted HIV transmission

Impact of pre-adapted HIV transmission

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Human leukocyte antigen class I (HLA)-restricted CD8(+) T lymphocyte (CTL) responses are crucial to HIV-1 control. Although HIV can evade these responses, the longer-term impact of viral escape mutants remains unclear, as these variants can also reduce intrinsic viral fitness. To address this, we he...

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Bibliographic Details
Main Authors: Carlson, J, Du, V, Pfeifer, N, Bansal, A, Tan, V, Power, K, Brumme, C, Kreimer, A, DeZiel, C, Fusi, N, Schaefer, M, Brockman, M, Gilmour, J, Price, M, Kilembe, W, Haubrich, R, John, M, Mallal, S, Shapiro, R, Frater, J, Harrigan, P, Ndung'u, T, Allen, S, Heckerman, D, Sidney, J, Allen, T, Goulder, P, Brumme, Z, Hunter, E, Goepfert, P
Format: Journal article
Language:English
Published: Nature Publishing Group 2016

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