Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery - A systematic review.

<h4>Background</h4> <p>Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approaches resulting in higher post-operative opiate cons...

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Main Authors: Mohammad, H, Trivella, M, Hamilton, T, Strickland, L, Murray, D, Pandit, H
Format: Journal article
Language:English
Published: BioMed Central 2017
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author Mohammad, H
Trivella, M
Hamilton, T
Strickland, L
Murray, D
Pandit, H
author_facet Mohammad, H
Trivella, M
Hamilton, T
Strickland, L
Murray, D
Pandit, H
author_sort Mohammad, H
collection OXFORD
description <h4>Background</h4> <p>Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approaches resulting in higher post-operative opiate consumption. The effect of corticosteroids as an adjunct for post-operative pain control remains undefined.</p> <h4>Methods</h4> <p>The databases MEDLINE, EMBASE and CENTRAL (Cochrane library) will be searched from their inception to present using broad search criteria for eligible randomised/quasi-randomised controlled trials investigating perioperative corticosteroid adjunctive use in elective knee surgery. Meta-analyses will be conducted according to the recommendations from the Cochrane Handbook for Systematic Reviews of Interventions.</p> <h4>Discussion</h4> <p>This systematic review of the perioperative adjunctive use of corticosteroids will assess the analgesic effects, post-operative nausea and vomiting, opiate consumption, infection rates and time till discharge and assess whether adjunctive corticosteroids should be encouraged in elective knee surgery.</p>
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spelling oxford-uuid:f3aa1658-df10-4753-8058-40fefb18365c2022-03-27T12:13:48ZPerioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery - A systematic review.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f3aa1658-df10-4753-8058-40fefb18365cEnglishSymplectic Elements at OxfordBioMed Central2017Mohammad, HTrivella, MHamilton, TStrickland, LMurray, DPandit, H <h4>Background</h4> <p>Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approaches resulting in higher post-operative opiate consumption. The effect of corticosteroids as an adjunct for post-operative pain control remains undefined.</p> <h4>Methods</h4> <p>The databases MEDLINE, EMBASE and CENTRAL (Cochrane library) will be searched from their inception to present using broad search criteria for eligible randomised/quasi-randomised controlled trials investigating perioperative corticosteroid adjunctive use in elective knee surgery. Meta-analyses will be conducted according to the recommendations from the Cochrane Handbook for Systematic Reviews of Interventions.</p> <h4>Discussion</h4> <p>This systematic review of the perioperative adjunctive use of corticosteroids will assess the analgesic effects, post-operative nausea and vomiting, opiate consumption, infection rates and time till discharge and assess whether adjunctive corticosteroids should be encouraged in elective knee surgery.</p>
spellingShingle Mohammad, H
Trivella, M
Hamilton, T
Strickland, L
Murray, D
Pandit, H
Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery - A systematic review.
title Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery - A systematic review.
title_full Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery - A systematic review.
title_fullStr Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery - A systematic review.
title_full_unstemmed Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery - A systematic review.
title_short Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery - A systematic review.
title_sort perioperative adjuvant corticosteroids for post operative analgesia in elective knee surgery a systematic review
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