Structural basis for protein-protein interactions in the 14-3-3 protein family.

The seven members of the human 14-3-3 protein family regulate a diverse range of cell signaling pathways by formation of protein-protein complexes with signaling proteins that contain phosphorylated Ser/Thr residues within specific sequence motifs. Previously, crystal structures of three 14-3-3 isof...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Yang, X, Lee, W, Sobott, F, Papagrigoriou, E, Robinson, C, Grossmann, J, Sundström, M, Doyle, D, Elkins, J
Format: Journal article
Sprache:English
Veröffentlicht: 2006