The biology of ADGRL4/ELTD1 in angiogenesis and tumour development
ADGRL4/ELTD1 is an orphan adhesion G protein-coupled receptor that is expressed in both endothelial cells and vascular smooth muscle cells. ELTD1 expression was significantly upregulated in the tumour vasculature and previous studies in our laboratories identified ELTD1 as a novel regulator of tu...
Main Author: | Ang, KH |
---|---|
Other Authors: | Harris, A |
Format: | Thesis |
Language: | English |
Published: |
2019
|
Subjects: |
Similar Items
-
The biology of ELTD1/ADGRL4: a novel regulator of tumour angiogenesis
by: Favara, DM
Published: (2017) -
ADGRL4/ELTD1 is a highly conserved angiogenesis-associated orphan adhesion GPCR that emerged with the first vertebrates and comprises 3 evolutionary variants
by: Favara, D, et al.
Published: (2019) -
ELTD1 is present in extracellular vesicles derived from endothelial cells as a cleaved extracellular domain which induces in vivo angiogenesis
by: Helen Sheldon, et al.
Published: (2022-08-01) -
ADGRL4/ELTD1 silencing in endothelial cells induces ACLY and SLC25A1 and alters the cellular metabolic profile
by: Favara, DM, et al.
Published: (2019) -
Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4).
by: Shun Lu, et al.
Published: (2017-01-01)