Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis.

The manifestation of coronary artery disease (CAD) follows a well-choreographed series of events that includes damage of arterial endothelial cells and deposition of lipids in the sub-endothelial layers. Genome-wide association studies (GWAS) of multiple populations with distinctive genetic and life...

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Main Authors: Hager, J, Kamatani, Y, Cazier, J, Youhanna, S, Ghassibe-Sabbagh, M, Platt, D, Abchee, AB, Romanos, J, Khazen, G, Othman, R, Badro, D, Haber, M, Salloum, A, Douaihy, B, Shasha, N, Kabbani, S, Sbeite, H, Chammas, E, el Bayeh, H, Rousseau, F, Zelenika, D, Gut, I, Lathrop, M, Farrall, M, Gauguier, D, Zalloua, P
Format: Journal article
Language:English
Published: Public Library of Science 2012