Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells

The intracellular environment hosts a large number of cancer- and other disease-relevant human proteins. Targeting these with internalized antibodies would allow therapeutic modulation of hitherto undruggable pathways, such as those mediated by protein–protein interactions. However, one of the major...

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Autors principals: Tietz, O, Cortezon Tamarit, F, Chalk, R, Able, S, Vallis, K
Format: Journal article
Idioma:English
Publicat: Springer Nature 2022