Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study.

OBJECTIVE: To compare perinatal outcomes, maternal outcomes, and interventions in labour by planned place of birth at the start of care in labour for women with low risk pregnancies. DESIGN: Prospective cohort study. SETTING: England: all NHS trusts providing intrapartum care at home, all freestand...

Full description

Bibliographic Details
Main Authors: Brocklehurst, P, Hardy, P, Hollowell, J, Linsell, L, Macfarlane, A, McCourt, C, Marlow, N, Miller, A, Newburn, M, Petrou, S, Puddicombe, D, Redshaw, M, Rowe, R, Sandall, J, Silverton, L, Stewart, M
Format: Journal article
Language:English
Published: 2011
_version_ 1826304902194790400
author Brocklehurst, P
Hardy, P
Hollowell, J
Linsell, L
Macfarlane, A
McCourt, C
Marlow, N
Miller, A
Newburn, M
Petrou, S
Puddicombe, D
Redshaw, M
Rowe, R
Sandall, J
Silverton, L
Stewart, M
author_facet Brocklehurst, P
Hardy, P
Hollowell, J
Linsell, L
Macfarlane, A
McCourt, C
Marlow, N
Miller, A
Newburn, M
Petrou, S
Puddicombe, D
Redshaw, M
Rowe, R
Sandall, J
Silverton, L
Stewart, M
author_sort Brocklehurst, P
collection OXFORD
description OBJECTIVE: To compare perinatal outcomes, maternal outcomes, and interventions in labour by planned place of birth at the start of care in labour for women with low risk pregnancies. DESIGN: Prospective cohort study. SETTING: England: all NHS trusts providing intrapartum care at home, all freestanding midwifery units, all alongside midwifery units (midwife led units on a hospital site with an obstetric unit), and a stratified random sample of obstetric units. PARTICIPANTS: 64,538 eligible women with a singleton, term (≥37 weeks gestation), and "booked" pregnancy who gave birth between April 2008 and April 2010. Planned caesarean sections and caesarean sections before the onset of labour and unplanned home births were excluded. MAIN OUTCOME MEASURE: A composite primary outcome of perinatal mortality and intrapartum related neonatal morbidities (stillbirth after start of care in labour, early neonatal death, neonatal encephalopathy, meconium aspiration syndrome, brachial plexus injury, fractured humerus, or fractured clavicle) was used to compare outcomes by planned place of birth at the start of care in labour (at home, freestanding midwifery units, alongside midwifery units, and obstetric units). RESULTS: There were 250 primary outcome events and an overall weighted incidence of 4.3 per 1000 births (95% CI 3.3 to 5.5). Overall, there were no significant differences in the adjusted odds of the primary outcome for any of the non-obstetric unit settings compared with obstetric units. For nulliparous women, the odds of the primary outcome were higher for planned home births (adjusted odds ratio 1.75, 95% CI 1.07 to 2.86) but not for either midwifery unit setting. For multiparous women, there were no significant differences in the incidence of the primary outcome by planned place of birth. Interventions during labour were substantially lower in all non-obstetric unit settings. Transfers from non-obstetric unit settings were more frequent for nulliparous women (36% to 45%) than for multiparous women (9% to 13%). CONCLUSIONS: The results support a policy of offering healthy women with low risk pregnancies a choice of birth setting. Women planning birth in a midwifery unit and multiparous women planning birth at home experience fewer interventions than those planning birth in an obstetric unit with no impact on perinatal outcomes. For nulliparous women, planned home births also have fewer interventions but have poorer perinatal outcomes.
first_indexed 2024-03-07T06:24:45Z
format Journal article
id oxford-uuid:f3e460f8-9c8c-49bd-aab1-f226514a2baa
institution University of Oxford
language English
last_indexed 2024-03-07T06:24:45Z
publishDate 2011
record_format dspace
spelling oxford-uuid:f3e460f8-9c8c-49bd-aab1-f226514a2baa2022-03-27T12:15:36ZPerinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f3e460f8-9c8c-49bd-aab1-f226514a2baaEnglishSymplectic Elements at Oxford2011Brocklehurst, PHardy, PHollowell, JLinsell, LMacfarlane, AMcCourt, CMarlow, NMiller, ANewburn, MPetrou, SPuddicombe, DRedshaw, MRowe, RSandall, JSilverton, LStewart, M OBJECTIVE: To compare perinatal outcomes, maternal outcomes, and interventions in labour by planned place of birth at the start of care in labour for women with low risk pregnancies. DESIGN: Prospective cohort study. SETTING: England: all NHS trusts providing intrapartum care at home, all freestanding midwifery units, all alongside midwifery units (midwife led units on a hospital site with an obstetric unit), and a stratified random sample of obstetric units. PARTICIPANTS: 64,538 eligible women with a singleton, term (≥37 weeks gestation), and "booked" pregnancy who gave birth between April 2008 and April 2010. Planned caesarean sections and caesarean sections before the onset of labour and unplanned home births were excluded. MAIN OUTCOME MEASURE: A composite primary outcome of perinatal mortality and intrapartum related neonatal morbidities (stillbirth after start of care in labour, early neonatal death, neonatal encephalopathy, meconium aspiration syndrome, brachial plexus injury, fractured humerus, or fractured clavicle) was used to compare outcomes by planned place of birth at the start of care in labour (at home, freestanding midwifery units, alongside midwifery units, and obstetric units). RESULTS: There were 250 primary outcome events and an overall weighted incidence of 4.3 per 1000 births (95% CI 3.3 to 5.5). Overall, there were no significant differences in the adjusted odds of the primary outcome for any of the non-obstetric unit settings compared with obstetric units. For nulliparous women, the odds of the primary outcome were higher for planned home births (adjusted odds ratio 1.75, 95% CI 1.07 to 2.86) but not for either midwifery unit setting. For multiparous women, there were no significant differences in the incidence of the primary outcome by planned place of birth. Interventions during labour were substantially lower in all non-obstetric unit settings. Transfers from non-obstetric unit settings were more frequent for nulliparous women (36% to 45%) than for multiparous women (9% to 13%). CONCLUSIONS: The results support a policy of offering healthy women with low risk pregnancies a choice of birth setting. Women planning birth in a midwifery unit and multiparous women planning birth at home experience fewer interventions than those planning birth in an obstetric unit with no impact on perinatal outcomes. For nulliparous women, planned home births also have fewer interventions but have poorer perinatal outcomes.
spellingShingle Brocklehurst, P
Hardy, P
Hollowell, J
Linsell, L
Macfarlane, A
McCourt, C
Marlow, N
Miller, A
Newburn, M
Petrou, S
Puddicombe, D
Redshaw, M
Rowe, R
Sandall, J
Silverton, L
Stewart, M
Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study.
title Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study.
title_full Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study.
title_fullStr Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study.
title_full_unstemmed Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study.
title_short Perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies: the Birthplace in England national prospective cohort study.
title_sort perinatal and maternal outcomes by planned place of birth for healthy women with low risk pregnancies the birthplace in england national prospective cohort study
work_keys_str_mv AT brocklehurstp perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT hardyp perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT hollowellj perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT linselll perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT macfarlanea perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT mccourtc perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT marlown perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT millera perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT newburnm perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT petrous perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT puddicombed perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT redshawm perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT rower perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT sandallj perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT silvertonl perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy
AT stewartm perinatalandmaternaloutcomesbyplannedplaceofbirthforhealthywomenwithlowriskpregnanciesthebirthplaceinenglandnationalprospectivecohortstudy