THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
Những tác giả chính: | Shaw, J, Hatano, H, Cauli, A, Giles, J, McHugh, K, Mathieu, A, Bowness, P, Kollnberger, S |
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Định dạng: | Conference item |
Được phát hành: |
2013
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HLA-B*2709 FORMS LESS CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN ARTHRITIS-ASSOCIATED HLA-B*2705
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The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09.
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Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.
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