The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy.

From 1991-2002, we treated 58 patients with multiple sclerosis (MS) using the humanised monoclonal antibody, Campath-1H, which causes prolonged T lymphocyte depletion. Clinical and surrogate markers of inflammation were suppressed. In both the relapsing-remitting (RR) and secondary progressive (SP)...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Coles, A, Cox, A, Le Page, E, Jones, J, Trip, SA, Deans, J, Seaman, S, Miller, D, Hale, G, Waldmann, H, Compston, D
Format: Journal article
Sprache:English
Veröffentlicht: 2006