Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review

Hypoxia is a feature of most solid tumours and predicts for poor prognosis. In radiobiological hypoxia (<0.1% O2) cells become up to three times more resistant to radiation. The biological response to radiobiological hypoxia is one of few physiologically relevant stresses that activates both the...

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Main Authors: Bolland, H, Ma, T, Ramlee, S, Ramadan, K, Hammond, E
格式: Journal article
语言:English
出版: Portland Press 2021