Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide].
X-ray crystallographic analysis of the title hydro-bromide salt, C(10)H(20)N(+)·Br(-), of (1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol defines the absolute and relative stereochemistry at the five chiral centres in steviamine, a new class of polyhydroxy-lated indolizid...
| Главные авторы: | , , , , , , , , , , |
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| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
2009
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| _version_ | 1826304948718010368 |
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| author | Thompson, A Michalik, A Nash, R Wilson, F van Well, R Johnson, P Fleet, G Yu, C Hu, X Cooper, R Watkin, D |
| author_facet | Thompson, A Michalik, A Nash, R Wilson, F van Well, R Johnson, P Fleet, G Yu, C Hu, X Cooper, R Watkin, D |
| author_sort | Thompson, A |
| collection | OXFORD |
| description | X-ray crystallographic analysis of the title hydro-bromide salt, C(10)H(20)N(+)·Br(-), of (1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol defines the absolute and relative stereochemistry at the five chiral centres in steviamine, a new class of polyhydroxy-lated indolizidine alkaloid isolated from Stevia rebaudiana (Asteraceae) leaves. In the crystal structure, mol-ecules are linked by inter-molecular O-H⋯Br and N-H⋯Br hydrogen bonds, forming double chains around the twofold screw axes along the b-axis direction. Intra-molecular O-H⋯O inter-actions occur. |
| first_indexed | 2024-03-07T06:25:28Z |
| format | Journal article |
| id | oxford-uuid:f423624a-f931-4268-8cba-9bd6df4a0a9f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:25:28Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:f423624a-f931-4268-8cba-9bd6df4a0a9f2022-03-27T12:17:29ZSteviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide].Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f423624a-f931-4268-8cba-9bd6df4a0a9fEnglishSymplectic Elements at Oxford2009Thompson, AMichalik, ANash, RWilson, Fvan Well, RJohnson, PFleet, GYu, CHu, XCooper, RWatkin, DX-ray crystallographic analysis of the title hydro-bromide salt, C(10)H(20)N(+)·Br(-), of (1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol defines the absolute and relative stereochemistry at the five chiral centres in steviamine, a new class of polyhydroxy-lated indolizidine alkaloid isolated from Stevia rebaudiana (Asteraceae) leaves. In the crystal structure, mol-ecules are linked by inter-molecular O-H⋯Br and N-H⋯Br hydrogen bonds, forming double chains around the twofold screw axes along the b-axis direction. Intra-molecular O-H⋯O inter-actions occur. |
| spellingShingle | Thompson, A Michalik, A Nash, R Wilson, F van Well, R Johnson, P Fleet, G Yu, C Hu, X Cooper, R Watkin, D Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide]. |
| title | Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide]. |
| title_full | Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide]. |
| title_fullStr | Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide]. |
| title_full_unstemmed | Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide]. |
| title_short | Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide]. |
| title_sort | steviamine a new class of indolizidine alkaloid 1r 2s 3r 5r 8ar 3 hydroxy meth yl 5 methyl octa hydro indolizine 1 2 diol hydro bromide |
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