A carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animals
A magnetic resonance (MR)-, computed tomography (CT)-, single-photon emission computed tomography (SPECT)-, and positron emission tomography (PET)-compatible carbon-fiber sheet resistor for temperature maintenance in small animals where space limitations prevent the use of circulating fluids was dev...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
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Grapho Publications
2019
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| _version_ | 1797103829647360000 |
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| author | Kersemans, V Gilchrist, S Wallington, S Allen, PD Gomes, AL Dias, GM Cornelissen, B Kinchesh, P Smart, SC |
| author_facet | Kersemans, V Gilchrist, S Wallington, S Allen, PD Gomes, AL Dias, GM Cornelissen, B Kinchesh, P Smart, SC |
| author_sort | Kersemans, V |
| collection | OXFORD |
| description | A magnetic resonance (MR)-, computed tomography (CT)-, single-photon emission computed tomography (SPECT)-, and positron emission tomography (PET)-compatible carbon-fiber sheet resistor for temperature maintenance in small animals where space limitations prevent the use of circulating fluids was developed. A 250 Ω carbon-fiber sheet resistor was mounted to the underside of an imaging cradle. Alternating current, operating at 99 kHz, and with a power of 1-2 W, was applied to the resistor providing a cradle base temperature of ∼37°C. Temperature control was implemented with a proportional–integral–derivative controller, and temperature maintenance was demonstrated in 4 mice positioned in both MR and PET/SPECT/CT scanners. MR and CT compatibility were also shown, and multimodal MR-CT-PET-SPECT imaging of the mouse abdomen was performed in vivo. Core temperature was maintained at 35.5°C ± 0.2°C. No line-shape, frequency, or image distortions attributable to the current flow through the heater were observed on MR. Upon CT imaging, no heater-related artifacts were observed when carbon-fiber was used. Multimodal imaging was performed and images could be easily coregistered, displayed, analyzed, and presented. Carbon fiber sheet resistors powered with high-frequency alternating current allow homeothermic maintenance that is compatible with multimodal imaging. The heater is small, and it is easy to produce and integrate into multimodal imaging cradles. |
| first_indexed | 2024-03-07T06:25:32Z |
| format | Journal article |
| id | oxford-uuid:f42b0743-4ff4-4f0c-a841-307af9ffa0de |
| institution | University of Oxford |
| last_indexed | 2024-03-07T06:25:32Z |
| publishDate | 2019 |
| publisher | Grapho Publications |
| record_format | dspace |
| spelling | oxford-uuid:f42b0743-4ff4-4f0c-a841-307af9ffa0de2022-03-27T12:17:48ZA carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animalsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f42b0743-4ff4-4f0c-a841-307af9ffa0deSymplectic Elements at OxfordGrapho Publications2019Kersemans, VGilchrist, SWallington, SAllen, PDGomes, ALDias, GMCornelissen, BKinchesh, PSmart, SCA magnetic resonance (MR)-, computed tomography (CT)-, single-photon emission computed tomography (SPECT)-, and positron emission tomography (PET)-compatible carbon-fiber sheet resistor for temperature maintenance in small animals where space limitations prevent the use of circulating fluids was developed. A 250 Ω carbon-fiber sheet resistor was mounted to the underside of an imaging cradle. Alternating current, operating at 99 kHz, and with a power of 1-2 W, was applied to the resistor providing a cradle base temperature of ∼37°C. Temperature control was implemented with a proportional–integral–derivative controller, and temperature maintenance was demonstrated in 4 mice positioned in both MR and PET/SPECT/CT scanners. MR and CT compatibility were also shown, and multimodal MR-CT-PET-SPECT imaging of the mouse abdomen was performed in vivo. Core temperature was maintained at 35.5°C ± 0.2°C. No line-shape, frequency, or image distortions attributable to the current flow through the heater were observed on MR. Upon CT imaging, no heater-related artifacts were observed when carbon-fiber was used. Multimodal imaging was performed and images could be easily coregistered, displayed, analyzed, and presented. Carbon fiber sheet resistors powered with high-frequency alternating current allow homeothermic maintenance that is compatible with multimodal imaging. The heater is small, and it is easy to produce and integrate into multimodal imaging cradles. |
| spellingShingle | Kersemans, V Gilchrist, S Wallington, S Allen, PD Gomes, AL Dias, GM Cornelissen, B Kinchesh, P Smart, SC A carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animals |
| title | A carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animals |
| title_full | A carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animals |
| title_fullStr | A carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animals |
| title_full_unstemmed | A carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animals |
| title_short | A carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animals |
| title_sort | carbon fiber sheet resistor for mr ct spect and pet compatible temperature maintenance in small animals |
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