IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-gamma and nitric oxide synthetase 2.

Resistance or susceptibility to most infectious diseases is strongly determined by the balance of type 1 vs type 2 cytokines produced during infection. However, for viruses, this scheme may be applicable only to infections with some cytopathic viruses, where IFN-gamma is considered as mandatory for...

詳細記述

書誌詳細
主要な著者: van Den Broek, M, Bachmann, M, Köhler, G, Barner, M, Escher, R, Zinkernagel, R, Kopf, M
フォーマット: Journal article
言語:English
出版事項: 2000