Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs

Integration of signalling downstream of individual receptor tyrosine kinases (RTKs) is crucial to fine‐tune cellular homeostasis during development and in pathological conditions, including breast cancer. However, how signalling integration is regulated and whether the endocytic fate of single recep...

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Hlavní autoři: Smith, MP, Ferguson, HR, Ferguson, J, Zindy, E, Kowalczyk, KM, Kedward, T, Bates, C, Parsons, J, Watson, J, Chandler, S, Fullwood, P, Warwood, S, Knight, D, Clarke, RB, Francavilla, C
Médium: Journal article
Jazyk:English
Vydáno: EMBO Press 2021