Epstein-Barr Virus associated gastric carcinoma
Epstein-Barr Virus (EBV) is a ubiquitous human herpesvirus associated with a variety of human malignancies including lymphoma and so-called lymphoepithelial carcinoma seen in a variety of sites, including the stomach. EBV has been detected in 5-20% of gastric carcinomas worldwide. Evidence is presen...
| Hoofdauteurs: | , |
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
2007
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| _version_ | 1826305031227310080 |
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| author | Oh, H Chetty, R |
| author_facet | Oh, H Chetty, R |
| author_sort | Oh, H |
| collection | OXFORD |
| description | Epstein-Barr Virus (EBV) is a ubiquitous human herpesvirus associated with a variety of human malignancies including lymphoma and so-called lymphoepithelial carcinoma seen in a variety of sites, including the stomach. EBV has been detected in 5-20% of gastric carcinomas worldwide. Evidence is presented which suggests that failure of EBV-specific immunity may play a role in the pathogenesis of EBV-associated malignancy. In this paper, we review the clinicopathologic features, molecular pathology, immunologic aspect, environmental factors in EBV-associated gastric carcinoma and lastly, EBV-targeted therapy. |
| first_indexed | 2024-03-07T06:26:41Z |
| format | Journal article |
| id | oxford-uuid:f48c0a8f-516e-4071-bc43-6dc6d46392eb |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:26:41Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:f48c0a8f-516e-4071-bc43-6dc6d46392eb2022-03-27T12:20:31ZEpstein-Barr Virus associated gastric carcinomaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f48c0a8f-516e-4071-bc43-6dc6d46392ebEnglishSymplectic Elements at Oxford2007Oh, HChetty, REpstein-Barr Virus (EBV) is a ubiquitous human herpesvirus associated with a variety of human malignancies including lymphoma and so-called lymphoepithelial carcinoma seen in a variety of sites, including the stomach. EBV has been detected in 5-20% of gastric carcinomas worldwide. Evidence is presented which suggests that failure of EBV-specific immunity may play a role in the pathogenesis of EBV-associated malignancy. In this paper, we review the clinicopathologic features, molecular pathology, immunologic aspect, environmental factors in EBV-associated gastric carcinoma and lastly, EBV-targeted therapy. |
| spellingShingle | Oh, H Chetty, R Epstein-Barr Virus associated gastric carcinoma |
| title | Epstein-Barr Virus associated gastric carcinoma |
| title_full | Epstein-Barr Virus associated gastric carcinoma |
| title_fullStr | Epstein-Barr Virus associated gastric carcinoma |
| title_full_unstemmed | Epstein-Barr Virus associated gastric carcinoma |
| title_short | Epstein-Barr Virus associated gastric carcinoma |
| title_sort | epstein barr virus associated gastric carcinoma |
| work_keys_str_mv | AT ohh epsteinbarrvirusassociatedgastriccarcinoma AT chettyr epsteinbarrvirusassociatedgastriccarcinoma |