MKP-1 knockout does not prevent glucocorticoid-induced bone disease in mice.

Glucocorticoid-induced osteoporosis (GCOP) is predominantly caused by inhibition of bone formation, resulting from a decrease in osteoblast numbers. Employing mouse (MBA-15.4) and human (MG-63) osteoblast cell lines, we previously found that the glucocorticoid (GC) dexamethasone (Dex) inhibits cellu...

詳細記述

書誌詳細
主要な著者: Conradie, M, Cato, A, Ferris, W, De Wet, H, Horsch, K, Hough, S
フォーマット: Journal article
言語:English
出版事項: 2011