Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein.
OBJECTIVE: Baseline concentrations of plasma C-reactive protein (CRP) are associated with coronary heart disease. Interleukin-6 (IL-6) regulates CRP gene expression; a promoter polymorphism (-174G/C) of the IL-6 gene has been shown to influence IL-6 transcription but the relationship between genoty...
Main Authors: | Vickers, M, Green, F, Terry, C, Mayosi, B, Julier, C, Lathrop, M, Ratcliffe, P, Watkins, H, Keavney, B |
---|---|
Format: | Journal article |
Jezik: | English |
Izdano: |
2002
|
Podobne knjige/članki
-
Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein
od: Vickers, M, et al.
Izdano: (1971) -
Plasma C-reactive protein (CRP), a novel cardiovascular risk factor, shows high heritability but no association with the-174 G/C polymorphism of the interleukin-6 (IL-6) gene in human families.
od: Keavney, B, et al.
Izdano: (2000) -
The genetic basis of variation in plasma fibrinogen and C-reactive protein levels
od: Mayosi, B, et al.
Izdano: (2000) -
Quantitative genetic study of plasma fibrinogen level and the-455 G/A polymorphism of the beta-fibrinogen gene using novel family-based association methods.
od: Mayosi, B, et al.
Izdano: (2000) -
Genotype at the -174G/C polymorphism of the interleukin-6 gene is associated with common carotid artery intimal-medial thickness: family study and meta-analysis.
od: Mayosi, B, et al.
Izdano: (2005)