Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein.

Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein.

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OBJECTIVE: Baseline concentrations of plasma C-reactive protein (CRP) are associated with coronary heart disease. Interleukin-6 (IL-6) regulates CRP gene expression; a promoter polymorphism (-174G/C) of the IL-6 gene has been shown to influence IL-6 transcription but the relationship between genoty...

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Detalles Bibliográficos
Autores principales: Vickers, M, Green, F, Terry, C, Mayosi, B, Julier, C, Lathrop, M, Ratcliffe, P, Watkins, H, Keavney, B
Formato: Journal article
Lenguaje:English
Publicado: 2002

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