Hydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines.
This article compares the diastereoselective epoxidation of acyclic and cyclic allylic alcohols, with the chemo- and diastereoselective olefinic oxidation of a range of acyclic and cyclic allylic amines. The diastereoselectivity in these systems is compared and a discussion about the origin of this...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Royal Society of Chemistry
2014
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| _version_ | 1797103937327726592 |
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| author | Davies, S Fletcher, A Thomson, J |
| author_facet | Davies, S Fletcher, A Thomson, J |
| author_sort | Davies, S |
| collection | OXFORD |
| description | This article compares the diastereoselective epoxidation of acyclic and cyclic allylic alcohols, with the chemo- and diastereoselective olefinic oxidation of a range of acyclic and cyclic allylic amines. The diastereoselectivity in these systems is compared and a discussion about the origin of this high diastereocontrol is also presented. The ammonium directed epoxidation methodology has been extended to more complex substrates and representative applications of this protocol in natural product synthesis are also summarised. |
| first_indexed | 2024-03-07T06:27:08Z |
| format | Journal article |
| id | oxford-uuid:f4b32790-246d-4651-81d0-c61c3972f0b5 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:27:08Z |
| publishDate | 2014 |
| publisher | Royal Society of Chemistry |
| record_format | dspace |
| spelling | oxford-uuid:f4b32790-246d-4651-81d0-c61c3972f0b52022-03-27T12:21:44ZHydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f4b32790-246d-4651-81d0-c61c3972f0b5EnglishSymplectic Elements at OxfordRoyal Society of Chemistry2014Davies, SFletcher, AThomson, JThis article compares the diastereoselective epoxidation of acyclic and cyclic allylic alcohols, with the chemo- and diastereoselective olefinic oxidation of a range of acyclic and cyclic allylic amines. The diastereoselectivity in these systems is compared and a discussion about the origin of this high diastereocontrol is also presented. The ammonium directed epoxidation methodology has been extended to more complex substrates and representative applications of this protocol in natural product synthesis are also summarised. |
| spellingShingle | Davies, S Fletcher, A Thomson, J Hydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines. |
| title | Hydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines. |
| title_full | Hydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines. |
| title_fullStr | Hydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines. |
| title_full_unstemmed | Hydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines. |
| title_short | Hydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines. |
| title_sort | hydrogen bond directed epoxidation diastereoselective olefinic oxidation of allylic alcohols and amines |
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