Occasional essay: Upper motor neuron syndrome in amyotrophic lateral sclerosis

The diagnosis of amyotrophic lateral sclerosis (ALS) requires recognition of both lower motor neuron (LMN) and upper motor neuron (UMN) dysfunction.1 However, classical UMN signs are frequently difficult to identify in ALS.2 LMN involvement is sensitively detected by electromyography (EMG),3 but, as...

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Main Authors: Swash, M, Burke, D, Turner, MR, Grosskreutz, J, Leigh, PN, deCarvalho, M, Kiernan, MC
格式: Journal article
语言:English
出版: BMJ Publishing Group 2020