Common genetic variation and the control of HIV-1 in humans.

Common genetic variation and the control of HIV-1 in humans.

To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants explaining down to 1.3% of the variability in viral load at set point. We...

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Príomhchruthaitheoirí: Fellay, J, Ge, D, Shianna, K, Colombo, S, Ledergerber, B, Cirulli, E, Urban, T, Zhang, K, Gumbs, C, Smith, J, Castagna, A, Cozzi-Lepri, A, De Luca, A, Easterbrook, P, Günthard, H, Mallal, S, Mussini, C, Dalmau, J, Martinez-Picado, J, Miro, J, Obel, N, Wolinsky, S, Martinson, J, Detels, R, Margolick, J, Jacobson, L, Descombes, P, Antonarakis, SE, Beckmann, J, O'Brien, S, Letvin, N, Mcmichael, A, Haynes, B, Carrington, M, Feng, S, Telenti, A, Goldstein, D
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science 2009

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