Insights into L-type heteromeric amino acid transporters

Two recent cryo-EM structures of the human L-type heteromeric amino acid transporter LAT1–CD98hc reveal surprising new insights into both amino acid transport in the human body and the roles of CD98hc as a cell-surface antigen and trafficking chaperone.

Podrobná bibliografie
Hlavní autor: Newstead, S
Médium: Journal article
Jazyk:English
Vydáno: Nature Research 2019
Popis
Shrnutí:Two recent cryo-EM structures of the human L-type heteromeric amino acid transporter LAT1–CD98hc reveal surprising new insights into both amino acid transport in the human body and the roles of CD98hc as a cell-surface antigen and trafficking chaperone.