Insights into L-type heteromeric amino acid transporters

Insights into L-type heteromeric amino acid transporters

Two recent cryo-EM structures of the human L-type heteromeric amino acid transporter LAT1–CD98hc reveal surprising new insights into both amino acid transport in the human body and the roles of CD98hc as a cell-surface antigen and trafficking chaperone.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας:	Newstead, S
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	Nature Research 2019

Παρόμοια τεκμήρια

Amino acid residues contributing to function of the heteromeric insect olfactory receptor complex.
ανά: Tatsuro Nakagawa, κ.ά.
Έκδοση: (2012-01-01)

Structural basis for proton coupled amino acid and peptide transport
ανά: Newstead, S
Έκδοση: (2017)

Proton-control of transitions in an amino-acid transporter
ανά: Wu, Z, κ.ά.
Έκδοση: (2019)

Proton-control of transitions in an amino-acid transporter
ανά: Wu, Z, κ.ά.
Έκδοση: (2019)

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains
ανά: Huaying Zhao, κ.ά.
Έκδοση: (2017-10-01)

Structural basis for amino acid transport by the CAT family of SLC7 transporters
ανά: Jungnickel, K, κ.ά.
Έκδοση: (2018)

Detergent-induced stabilization and improved 3D map of the human heteromeric amino acid transporter 4F2hc-LAT2.
ανά: Marcel Meury, κ.ά.
Έκδοση: (2014-01-01)

Interfering amino terminal peptides and functional implications for heteromeric gap junction formation
ανά: Richard David Veenstra, κ.ά.
Έκδοση: (2013-05-01)

Structural basis for amino acid transport by the CAT family of SLC7 transporters
ανά: Katharina E. J. Jungnickel, κ.ά.
Έκδοση: (2018-02-01)

Erratum: Interfering amino terminal peptides and functional implications for heteromeric gap junction formation
ανά: Eric C Beyer, κ.ά.
Έκδοση: (2013-07-01)

Heteromeric TRP Channels in Lung Inflammation
ανά: Meryam Zergane, κ.ά.
Έκδοση: (2021-07-01)

Modeling the kinetics of heteromeric potassium channels
ανά: Kees McGahan, κ.ά.
Έκδοση: (2022-11-01)

Functional validation of Heteromeric Kainate receptor models
ανά: Paramo, T, κ.ά.
Έκδοση: (2017)

Versatility and invariance in the evolution of homologous heteromeric interfaces.
ανά: Jessica Andreani, κ.ά.
Έκδοση: (2012-01-01)

L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism
ανά: Miku Sato, κ.ά.
Έκδοση: (2021-01-01)

Mathematical models of C-type and N-type inactivating heteromeric voltage gated potassium channels
ανά: Kees McGahan, κ.ά.
Έκδοση: (2024-10-01)

The L-type Amino Acid Transporter (LAT1) Expression in Patients with Scoliosis
ανά: Satoru Demura, κ.ά.
Έκδοση: (2022-07-01)

Amino Acid Transporters on Amino Acid Absorption, Transport and Distribution in Crops
ανά: Lu Liu, κ.ά.
Έκδοση: (2024-09-01)

Antibodies to heteromeric glycolipid complexes in Guillain-Barre syndrome
ανά: Rinaldi, S, κ.ά.
Έκδοση: (2013)

Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy.
ανά: Galban-Horcajo, F, κ.ά.
Έκδοση: (2013)

Heteromeric glycolipid complexes as modulators of autoantibody and lectin binding.
ανά: Rinaldi, S, κ.ά.
Έκδοση: (2010)

Functional analyses of heteromeric human PIEZO1 Channels.
ανά: Radhakrishnan Gnanasambandam, κ.ά.
Έκδοση: (2018-01-01)

Antibodies to heteromeric glycolipid complexes in Guillain-Barré syndrome.
ανά: Simon Rinaldi, κ.ά.
Έκδοση: (2013-01-01)

Biological significance of GPCR heteromerization in the neuro-endocrine system
ανά: Ralf eJockers, κ.ά.
Έκδοση: (2011-02-01)

Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy
ανά: Galban-Horcajo, F, κ.ά.
Έκδοση: (2013)

Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor
ανά: Elizabeth K. M. Johnstone, κ.ά.
Έκδοση: (2022-05-01)

Oligomerization of the heteromeric γ-aminobutyric acid receptor GABAB in a eukaryotic cell-free system
ανά: Jessica Ullrich, κ.ά.
Έκδοση: (2022-12-01)

L-type Amino Acid Transporter 1 as a Therapeutic Target in Pancreatic Cancer
ανά: Ragnar Norrsell BSc, κ.ά.
Έκδοση: (2024-04-01)

Therapeutic Potential for Intractable Asthma by Targeting L-Type Amino Acid Transporter 1
ανά: Keitaro Hayashi, κ.ά.
Έκδοση: (2022-04-01)

L-Type Amino Acid Transporter-1 Overexpression and Melphalan Sensitivity in Barrett's Adenocarcinoma
ανά: Jules Lin, κ.ά.
Έκδοση: (2004-01-01)

Dopamine D3 Receptor Heteromerization: Implications for Neuroplasticity and Neuroprotection
ανά: Federica Bono, κ.ά.
Έκδοση: (2020-07-01)

Conformational transitions and allosteric modulation in a heteromeric glycine receptor
ανά: Eric Gibbs, κ.ά.
Έκδοση: (2023-03-01)

Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons.
ανά: Raphael Rozenfeld, κ.ά.
Έκδοση: (2012-01-01)

Heteromerization Modulates mu Opioid Receptor Functional Properties in vivo
ανά: Muzeyyen Ugur, κ.ά.
Έκδοση: (2018-11-01)

Heteromeric Anopheline odorant receptors exhibit distinct channel properties.
ανά: Gregory M Pask, κ.ά.
Έκδοση: (2011-01-01)

Heteromerization of ciliary G protein-coupled receptors in the mouse brain.
ανά: Jill A Green, κ.ά.
Έκδοση: (2012-01-01)

Fluorescent non-canonical amino acid provides insight into the human serotonin transporter
ανά: Andreas Nygaard, κ.ά.
Έκδοση: (2024-10-01)

l-Type amino acid transporter 1-targeting nanoparticles for antisense oligonucleotide delivery to the CNS
ανά: Yu Na Lim, κ.ά.
Έκδοση: (2024-12-01)

Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1
ανά: Hiroki Okanishi, κ.ά.
Έκδοση: (2022-11-01)

Structure–activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1)
ανά: Sihui Chen, κ.ά.
Έκδοση: (2024-02-01)