Insights into L-type heteromeric amino acid transporters

Insights into L-type heteromeric amino acid transporters

Two recent cryo-EM structures of the human L-type heteromeric amino acid transporter LAT1–CD98hc reveal surprising new insights into both amino acid transport in the human body and the roles of CD98hc as a cell-surface antigen and trafficking chaperone.

ग्रंथसूची विवरण
मुख्य लेखक:	Newstead, S
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Nature Research 2019

समान संसाधन

Amino acid residues contributing to function of the heteromeric insect olfactory receptor complex.
द्वारा: Tatsuro Nakagawa, और अन्य
प्रकाशित: (2012-01-01)

Structural basis for proton coupled amino acid and peptide transport
द्वारा: Newstead, S
प्रकाशित: (2017)

Proton-control of transitions in an amino-acid transporter
द्वारा: Wu, Z, और अन्य
प्रकाशित: (2019)

Proton-control of transitions in an amino-acid transporter
द्वारा: Wu, Z, और अन्य
प्रकाशित: (2019)

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains
द्वारा: Huaying Zhao, और अन्य
प्रकाशित: (2017-10-01)

Structural basis for amino acid transport by the CAT family of SLC7 transporters
द्वारा: Jungnickel, K, और अन्य
प्रकाशित: (2018)

Detergent-induced stabilization and improved 3D map of the human heteromeric amino acid transporter 4F2hc-LAT2.
द्वारा: Marcel Meury, और अन्य
प्रकाशित: (2014-01-01)

Interfering amino terminal peptides and functional implications for heteromeric gap junction formation
द्वारा: Richard David Veenstra, और अन्य
प्रकाशित: (2013-05-01)

Structural basis for amino acid transport by the CAT family of SLC7 transporters
द्वारा: Katharina E. J. Jungnickel, और अन्य
प्रकाशित: (2018-02-01)

Erratum: Interfering amino terminal peptides and functional implications for heteromeric gap junction formation
द्वारा: Eric C Beyer, और अन्य
प्रकाशित: (2013-07-01)

Heteromeric TRP Channels in Lung Inflammation
द्वारा: Meryam Zergane, और अन्य
प्रकाशित: (2021-07-01)

Modeling the kinetics of heteromeric potassium channels
द्वारा: Kees McGahan, और अन्य
प्रकाशित: (2022-11-01)

Functional validation of Heteromeric Kainate receptor models
द्वारा: Paramo, T, और अन्य
प्रकाशित: (2017)

Versatility and invariance in the evolution of homologous heteromeric interfaces.
द्वारा: Jessica Andreani, और अन्य
प्रकाशित: (2012-01-01)

L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism
द्वारा: Miku Sato, और अन्य
प्रकाशित: (2021-01-01)

Mathematical models of C-type and N-type inactivating heteromeric voltage gated potassium channels
द्वारा: Kees McGahan, और अन्य
प्रकाशित: (2024-10-01)

The L-type Amino Acid Transporter (LAT1) Expression in Patients with Scoliosis
द्वारा: Satoru Demura, और अन्य
प्रकाशित: (2022-07-01)

Amino Acid Transporters on Amino Acid Absorption, Transport and Distribution in Crops
द्वारा: Lu Liu, और अन्य
प्रकाशित: (2024-09-01)

Antibodies to heteromeric glycolipid complexes in Guillain-Barre syndrome
द्वारा: Rinaldi, S, और अन्य
प्रकाशित: (2013)

Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy.
द्वारा: Galban-Horcajo, F, और अन्य
प्रकाशित: (2013)

Heteromeric glycolipid complexes as modulators of autoantibody and lectin binding.
द्वारा: Rinaldi, S, और अन्य
प्रकाशित: (2010)

Functional analyses of heteromeric human PIEZO1 Channels.
द्वारा: Radhakrishnan Gnanasambandam, और अन्य
प्रकाशित: (2018-01-01)

Antibodies to heteromeric glycolipid complexes in Guillain-Barré syndrome.
द्वारा: Simon Rinaldi, और अन्य
प्रकाशित: (2013-01-01)

Biological significance of GPCR heteromerization in the neuro-endocrine system
द्वारा: Ralf eJockers, और अन्य
प्रकाशित: (2011-02-01)

Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy
द्वारा: Galban-Horcajo, F, और अन्य
प्रकाशित: (2013)

Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor
द्वारा: Elizabeth K. M. Johnstone, और अन्य
प्रकाशित: (2022-05-01)

Oligomerization of the heteromeric γ-aminobutyric acid receptor GABAB in a eukaryotic cell-free system
द्वारा: Jessica Ullrich, और अन्य
प्रकाशित: (2022-12-01)

L-type Amino Acid Transporter 1 as a Therapeutic Target in Pancreatic Cancer
द्वारा: Ragnar Norrsell BSc, और अन्य
प्रकाशित: (2024-04-01)

Therapeutic Potential for Intractable Asthma by Targeting L-Type Amino Acid Transporter 1
द्वारा: Keitaro Hayashi, और अन्य
प्रकाशित: (2022-04-01)

L-Type Amino Acid Transporter-1 Overexpression and Melphalan Sensitivity in Barrett's Adenocarcinoma
द्वारा: Jules Lin, और अन्य
प्रकाशित: (2004-01-01)

Dopamine D3 Receptor Heteromerization: Implications for Neuroplasticity and Neuroprotection
द्वारा: Federica Bono, और अन्य
प्रकाशित: (2020-07-01)

Conformational transitions and allosteric modulation in a heteromeric glycine receptor
द्वारा: Eric Gibbs, और अन्य
प्रकाशित: (2023-03-01)

Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons.
द्वारा: Raphael Rozenfeld, और अन्य
प्रकाशित: (2012-01-01)

Heteromerization Modulates mu Opioid Receptor Functional Properties in vivo
द्वारा: Muzeyyen Ugur, और अन्य
प्रकाशित: (2018-11-01)

Heteromeric Anopheline odorant receptors exhibit distinct channel properties.
द्वारा: Gregory M Pask, और अन्य
प्रकाशित: (2011-01-01)

Heteromerization of ciliary G protein-coupled receptors in the mouse brain.
द्वारा: Jill A Green, और अन्य
प्रकाशित: (2012-01-01)

Fluorescent non-canonical amino acid provides insight into the human serotonin transporter
द्वारा: Andreas Nygaard, और अन्य
प्रकाशित: (2024-10-01)

l-Type amino acid transporter 1-targeting nanoparticles for antisense oligonucleotide delivery to the CNS
द्वारा: Yu Na Lim, और अन्य
प्रकाशित: (2024-12-01)

Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1
द्वारा: Hiroki Okanishi, और अन्य
प्रकाशित: (2022-11-01)

Structure–activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1)
द्वारा: Sihui Chen, और अन्य
प्रकाशित: (2024-02-01)