Genomic instability--the engine of tumorigenesis?
Human cancers harbour numerous mutations and it has been proposed that these result from some form of inherent genomic instability. Some cancers have proven genomic instability or features that are indicative of this. Inherited cancer syndromes exist that are caused by deficient DNA repair or chromo...
Main Authors: | Sieber, O, Heinimann, K, Tomlinson, I |
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格式: | Journal article |
语言: | English |
出版: |
2003
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