Growth hormone-releasing hormone in the diagnosis and treatment of growth hormone deficient children.
A growth hormone-releasing hormone (GHRH) has recently been extracted and synthesised, and appears to be identical to human hypothalamic GHRH. Immunoreactive GHRH is found in the venous blood of normal subjects and GH-deficient children, but is probably not hypothalamic in origin and therefore not i...
| Główni autorzy: | , , , |
|---|---|
| Format: | Journal article |
| Język: | English |
| Wydane: |
1986
|
| _version_ | 1826305155829596160 |
|---|---|
| author | Ross, R Grossman, A Besser, G Savage, M |
| author_facet | Ross, R Grossman, A Besser, G Savage, M |
| author_sort | Ross, R |
| collection | OXFORD |
| description | A growth hormone-releasing hormone (GHRH) has recently been extracted and synthesised, and appears to be identical to human hypothalamic GHRH. Immunoreactive GHRH is found in the venous blood of normal subjects and GH-deficient children, but is probably not hypothalamic in origin and therefore not important in GH regulation. GHRH is a potent specific stimulator of GH secretion in man, and provides a valuable diagnostic test in differentiating hypothalamic from pituitary causes of GH deficiency. Preliminary data suggests that GHRH may promote linear growth in some GH deficient children. GHRH may well prove an important alternative therapy for GH deficient children especially if depot preparations or intranasal administration prove effective. |
| first_indexed | 2024-03-07T06:28:35Z |
| format | Journal article |
| id | oxford-uuid:f52af9fb-b9e4-49ef-9ef7-dd58567ef999 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:28:35Z |
| publishDate | 1986 |
| record_format | dspace |
| spelling | oxford-uuid:f52af9fb-b9e4-49ef-9ef7-dd58567ef9992022-03-27T12:25:23ZGrowth hormone-releasing hormone in the diagnosis and treatment of growth hormone deficient children.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f52af9fb-b9e4-49ef-9ef7-dd58567ef999EnglishSymplectic Elements at Oxford1986Ross, RGrossman, ABesser, GSavage, MA growth hormone-releasing hormone (GHRH) has recently been extracted and synthesised, and appears to be identical to human hypothalamic GHRH. Immunoreactive GHRH is found in the venous blood of normal subjects and GH-deficient children, but is probably not hypothalamic in origin and therefore not important in GH regulation. GHRH is a potent specific stimulator of GH secretion in man, and provides a valuable diagnostic test in differentiating hypothalamic from pituitary causes of GH deficiency. Preliminary data suggests that GHRH may promote linear growth in some GH deficient children. GHRH may well prove an important alternative therapy for GH deficient children especially if depot preparations or intranasal administration prove effective. |
| spellingShingle | Ross, R Grossman, A Besser, G Savage, M Growth hormone-releasing hormone in the diagnosis and treatment of growth hormone deficient children. |
| title | Growth hormone-releasing hormone in the diagnosis and treatment of growth hormone deficient children. |
| title_full | Growth hormone-releasing hormone in the diagnosis and treatment of growth hormone deficient children. |
| title_fullStr | Growth hormone-releasing hormone in the diagnosis and treatment of growth hormone deficient children. |
| title_full_unstemmed | Growth hormone-releasing hormone in the diagnosis and treatment of growth hormone deficient children. |
| title_short | Growth hormone-releasing hormone in the diagnosis and treatment of growth hormone deficient children. |
| title_sort | growth hormone releasing hormone in the diagnosis and treatment of growth hormone deficient children |
| work_keys_str_mv | AT rossr growthhormonereleasinghormoneinthediagnosisandtreatmentofgrowthhormonedeficientchildren AT grossmana growthhormonereleasinghormoneinthediagnosisandtreatmentofgrowthhormonedeficientchildren AT besserg growthhormonereleasinghormoneinthediagnosisandtreatmentofgrowthhormonedeficientchildren AT savagem growthhormonereleasinghormoneinthediagnosisandtreatmentofgrowthhormonedeficientchildren |