Pathogen-induced inflammation is attenuated by the iminosugar MON-DNJ via modulation of the unfolded protein response
Sepsis is a life-threatening condition involving a dysregulated immune response to infectious agents that causes injury to host tissues and organs. Current treatments are limited to early administration of antibiotics and supportive care. While appealing, the strategy of targeted inhibition of indiv...
Main Authors: | Sayce, AC, Martinez, FO, Tyrrell, BE, Perera, N, Hill, ML, Dwek, RA, Miller, JL, Zitzmann, N |
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Format: | Journal article |
Language: | English |
Published: |
Wiley
2021
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