Plasma metabolomics implicates modified transfer RNAs and altered bioenergetics in the outcomes of pulmonary arterial hypertension

Plasma metabolomics implicates modified transfer RNAs and altered bioenergetics in the outcomes of pulmonary arterial hypertension

<strong>Background:</strong> Pulmonary arterial hypertension (PAH) is a heterogeneous disorder with high mortality. <strong>Methods:</strong> We conducted a comprehensive study of plasma metabolites using ultraperformance liquid chromatography mass spectrometry to identify p...

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Bibliografiske detaljer
Main Authors:	Rhodes, CJ, Ghataorhe, P, Wharton, J, Rue-Albrecht, KC, Hadinnapola, C, Watson, G, Bleda, M, Haimel, M, Coghlan, G, Corris, PA, Howard, LS, Kiely, DG, Peacock, AJ, Pepke-Zaba, J, Toshner, MR, Wort, SJ, Gibbs, JSR, Lawrie, A, Gräf, S, Morrell, NW, Wilkins, MR
Format:	Journal article
Sprog:	English
Udgivet:	American Heart Association 2016

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Bioenergetics /
af: Ernster, L., editor 652940
Udgivet: (1984)

Bioenergetics /
af: Graber, P, et al.
Udgivet: (1997)

Chronic Thromboembolic Pulmonary Hypertension: A Review of the Multifaceted Pathobiology
af: Hakim Ghani, et al.
Udgivet: (2023-12-01)

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
af: Stefan Gräf, et al.
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Bioelectrochemistry and bioenergetics
Udgivet: (1974)

CALIX[4]ARENES С-715 AND С-772 AS INSTRUMENTS OF INFLUENCE ON Са2+-TRANSPORT AND BIOENERGETICS IN MYOMETRIAL MITOCHONDRIA
af: I.S. FORYS, et al.
Udgivet: (2024-04-01)

The bioenergetics of paracoccus denitrificans
af: Kell, D
Udgivet: (1978)

The bioenergetic landscape of cancer
af: Elizabeth R.M. Zunica, et al.
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Udgivet: (2017-12-01)

Heterocyst Thylakoid Bioenergetics
af: Ann Magnuson
Udgivet: (2019-01-01)

Editorial: Environmental Bioenergetics
af: Anke M. Herrmann, et al.
Udgivet: (2019-09-01)

Editorial: Microbial Bioenergetics
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Udgivet: (2021-11-01)

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af: Heather M Wilkins, et al.
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The Gouy-Stodola Theorem in Bioenergetic Analysis of Living Systems (Irreversibility in Bioenergetics of Living Systems)
af: Umberto Lucia
Udgivet: (2014-09-01)

Biophysical and structural aspects of bioenergetics /
af: Wikstrom, Marten
Udgivet: (2005)

BBA : Bioenergetics [electronic journal]

Mitochondrial bioenergetics : methods and protocols /
af: Palmeira, Carlos M., et al.
Udgivet: (c201)

Bioenergetics primer for exercise science /
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Udgivet: (2008)

Bioenergetics : energy conservation and conversion /
af: Schafer, Gunter, 1935-, et al.
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Bioenergetic signatures of neurodevelopmental regression
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Evolutionary primacy of sodium bioenergetics
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Udgivet: (2008-04-01)

Bioenergetic Mechanisms of Seizure Control
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Udgivet: (2018-10-01)

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Udgivet: (2007)

Bioenergetic profiling of zebrafish embryonic development.
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Udgivet: (2011-01-01)

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