LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression
RNA-binding proteins (RBPs) bind to and post-transcriptionally regulate the stability of mRNAs. La-related protein 1 (LARP1) is a conserved RBP that interacts with poly-A-binding protein and is known to regulate 5′-terminal oligopyrimidine tract (TOP) mRNA translation. Here, we show that LARP1 is co...
Päätekijät: | Blagden, S, Bushell, M, Willis, A, Mura, M, Hopkins, T, Michael, T, Abd-Latip, N, Curry, E, Weir, J, Aboagye, E, Sturge, J, Jameson, C, Mauri, F |
---|---|
Aineistotyyppi: | Journal article |
Julkaistu: |
Nature Publishing Group: Open Access Hybrid Model Option B
2015
|
Samankaltaisia teoksia
-
The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer
Tekijä: Hopkins, T, et al.
Julkaistu: (2015) -
Telocinobufagin suppresses malignant metastasis of undifferentiated thyroid carcinoma via modulation of the LARP1‐mTOR pathway
Tekijä: Li‐Zhi Qiang, et al.
Julkaistu: (2025-03-01) -
Controversies around the function of LARP1
Tekijä: Berman, AJ, et al.
Julkaistu: (2020) -
The RNA-binding protein LARP1 is a cancer therapeutic target
Tekijä: Ghazaly, E, et al.
Julkaistu: (2017) -
Loss of LARP4B, an early event in the tumorigenesis of brain cancer?
Tekijä: Blagden, S, et al.
Julkaistu: (2016)