LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression

LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression

RNA-binding proteins (RBPs) bind to and post-transcriptionally regulate the stability of mRNAs. La-related protein 1 (LARP1) is a conserved RBP that interacts with poly-A-binding protein and is known to regulate 5′-terminal oligopyrimidine tract (TOP) mRNA translation. Here, we show that LARP1 is co...

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Автори: Blagden, S, Bushell, M, Willis, A, Mura, M, Hopkins, T, Michael, T, Abd-Latip, N, Curry, E, Weir, J, Aboagye, E, Sturge, J, Jameson, C, Mauri, F
Формат: Journal article
Опубліковано: Nature Publishing Group: Open Access Hybrid Model Option B 2015

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