Factor inhibiting HIF can catalyse two asparaginyl-hydroxylations in VNVN motifs of ankyrin fold proteins

Factor inhibiting HIF can catalyse two asparaginyl-hydroxylations in VNVN motifs of ankyrin fold proteins

The aspariginyl-hydroxylase human Factor Inhibiting HIF (FIH) is an important regulator of the transcriptional activity of hypoxia inducible factor (HIF). FIH also catalyses the hydroxylation of asparaginyl and other residues in ankyrin repeat domain (ARD) containing proteins, including apoptosis st...

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Bibliographic Details
Main Authors:	Leissing, TM, Hardy, AP, Chan, H, Wang, Y, Tumber, A, Chowdhury, R, Fang, P, Coleman, ML, Cockman, ME, Kramer, HB, Berridge, G, Fischer, R, Kessler, B, Ratcliffe, PJ, Lu, X, Schofield, CJ
Format:	Journal article
Language:	English
Published:	Elsevier 2022

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