Factor inhibiting HIF can catalyse two asparaginyl-hydroxylations in VNVN motifs of ankyrin fold proteins

Factor inhibiting HIF can catalyse two asparaginyl-hydroxylations in VNVN motifs of ankyrin fold proteins

The aspariginyl-hydroxylase human Factor Inhibiting HIF (FIH) is an important regulator of the transcriptional activity of hypoxia inducible factor (HIF). FIH also catalyses the hydroxylation of asparaginyl and other residues in ankyrin repeat domain (ARD) containing proteins, including apoptosis st...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Leissing, TM, Hardy, AP, Chan, H, Wang, Y, Tumber, A, Chowdhury, R, Fang, P, Coleman, ML, Cockman, ME, Kramer, HB, Berridge, G, Fischer, R, Kessler, B, Ratcliffe, PJ, Lu, X, Schofield, CJ
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Elsevier 2022

Những quyển sách tương tự

FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
Bằng: Cockman, M, et al.
Được phát hành: (2009)

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.
Bằng: Coleman, M, et al.
Được phát hành: (2007)

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Bằng: Cockman, M, et al.
Được phát hành: (2006)

Biochemical and structural insights into FIH-catalysed hydroxylation of transient receptor potential ankyrin repeat domains
Bằng: Saward, B, et al.
Được phát hành: (2022)

Asparaginyl beta-hydroxylation of proteins containing ankyrin repeat domains influences their stability and function.
Bằng: Hardy, A, et al.
Được phát hành: (2009)

Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
Bằng: Cockman, M, et al.
Được phát hành: (2009)

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.
Bằng: Yang, M, et al.
Được phát hành: (2011)

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803.
Bằng: McNeill, L, et al.
Được phát hành: (2002)

Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold.
Bằng: Kelly, L, et al.
Được phát hành: (2009)

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
Bằng: Chan, M, et al.
Được phát hành: (2016)

Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6
Bằng: Cockman, ME, et al.
Được phát hành: (2022)

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.
Bằng: Yang, M, et al.
Được phát hành: (2011)

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.
Bằng: Masson, N, et al.
Được phát hành: (2003)

HIF hydroxylation and cellular oxygen sensing.
Bằng: Metzen, E, et al.
Được phát hành: (2004)

JmjC catalysed histone H2a N -methyl arginine demethylation and C4-arginine hydroxylation reveals importance of sequence-reactivity relationships
Bằng: Bonnici, J, et al.
Được phát hành: (2024)

Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation
Bằng: Singleton, R, et al.
Được phát hành: (2011)

Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation.
Bằng: Singleton, R, et al.
Được phát hành: (2011)

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy.
Bằng: Loenarz, C, et al.
Được phát hành: (2014)

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
Bằng: Markolovic, S, et al.
Được phát hành: (2018)

Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.
Bằng: Grosfeld, A, et al.
Được phát hành: (2007)

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Bằng: Stolze, I, et al.
Được phát hành: (2004)

Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.
Bằng: Webby, C, et al.
Được phát hành: (2009)

Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.
Bằng: Kageyama, Y, et al.
Được phát hành: (2004)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
Bằng: Cockman, M, et al.
Được phát hành: (2019)

JmjC catalysed histone H2a N-methyl arginine demethylation and C4-arginine hydroxylation reveals importance of sequence-reactivity relationships
Bằng: Joanna Bonnici, et al.
Được phát hành: (2024-11-01)

Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.
Bằng: Lancaster, D, et al.
Được phát hành: (2004)

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
Bằng: Jaakkola, P, et al.
Được phát hành: (2001)

Oxygen sensing by HIF hydroxylases.
Bằng: Schofield, C, et al.
Được phát hành: (2004)

Signalling hypoxia by HIF hydroxylases.
Bằng: Schofield, C, et al.
Được phát hành: (2005)

Molecular and Cellular Mechanisms of HIF Prolyl Hydroxylase inhibitors in Clinical Trials
Bằng: Yeh, TL, et al.
Được phát hành: (2017)

Mechanical anisotropy of ankyrin repeats.
Bằng: Lee, W, et al.
Được phát hành: (2012)

Mechanical anisotropy of ankyrin repeats
Bằng: Lee, W, et al.
Được phát hành: (2012)

Broaden the applications of peptidyl asparaginyl ligases
Bằng: Xia, Yiyin
Được phát hành: (2023)

Inhibition of the oxygen-sensing asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor: a potential hypoxia response modulating strategy
Bằng: Wu, Y, et al.
Được phát hành: (2021)

Purified recombinant hARD1 does not catalyse acetylation of Lys532 of HIF-1alpha fragments in vitro.
Bằng: Murray-Rust, T, et al.
Được phát hành: (2006)

MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).
Bằng: Webb, J, et al.
Được phát hành: (2009)

Structure–activity relationship and crystallographic studies on 4-hydroxypyrimidine HIF prolyl hydroxylase domain inhibitors
Bằng: Holt-Martyn, JP, et al.
Được phát hành: (2019)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
Bằng: Matthew E Cockman, et al.
Được phát hành: (2019-09-01)

Protein engineering using asparaginyl peptide ligases
Bằng: Wang, Zhen
Được phát hành: (2023)

Turning an asparaginyl endopeptidase into a peptide ligase
Bằng: Hemu, Xinya, et al.
Được phát hành: (2021)