Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.

Hypoxia-inducible factor (HIF) mediates a large number of transcriptional responses to hypoxia and has an important role in processes that include angiogenesis and erythropoiesis. The HIF DNA binding complex consists of 2 basic-helix-loop-helix PAS proteins designated alpha and beta subunits. Regula...

Bibliográfalaš dieđut
Váldodahkkit:	Vaux, E, Metzen, E, Yeates, K, Ratcliffe, P
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2001

Geahča maid

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The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia
Dahkki: Robert B. Hamanaka, et al.
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Nitrite protects mitochondrial structure and function under hypoxia
Dahkki: Ratcliffe, R, et al.
Almmustuhtton: (2016)

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.
Dahkki: Masson, N, et al.
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From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
Dahkki: Ratcliffe, P
Almmustuhtton: (2002)

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
Dahkki: Maxwell, P, et al.
Almmustuhtton: (1999)

The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9.
Dahkki: Ulf Brockmeier, et al.
Almmustuhtton: (2011-04-01)

Mitochondrial respiratory chain protein co-regulation in the human brain
Dahkki: Caroline Trumpff, et al.
Almmustuhtton: (2022-05-01)

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression.
Dahkki: Wood, S, et al.
Almmustuhtton: (1998)

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences.
Dahkki: Ebert, B, et al.
Almmustuhtton: (1995)

Hypoxia and the regulation of gene expression.
Dahkki: Gleadle, J, et al.
Almmustuhtton: (1998)

Mitochondrial metabolism regulation and epigenetics in hypoxia
Dahkki: Madison Laird, et al.
Almmustuhtton: (2024-06-01)

The human side of hypoxia-inducible factor.
Dahkki: Smith, T, et al.
Almmustuhtton: (2008)

Blood-based mitochondrial respiratory chain function in major depression
Dahkki: Johan Fernström, et al.
Almmustuhtton: (2021-11-01)

Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression.
Dahkki: Ratcliffe, P, et al.
Almmustuhtton: (1998)

Mammalian oxygen sensing and hypoxia inducible factor-1
Dahkki: Wood, S, et al.
Almmustuhtton: (1997)

Hypoxia-induced mitochondrial stress granules
Dahkki: Chun-Ling Sun, et al.
Almmustuhtton: (2023-07-01)

HIF hydroxylation and cellular oxygen sensing.
Dahkki: Metzen, E, et al.
Almmustuhtton: (2004)

PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function
Dahkki: Lijie Dong, et al.
Almmustuhtton: (2021-02-01)

Hypoxia and hypoxia-inducible factor signals regulate the development, metabolism, and function of B cells
Dahkki: Jinwei Zhang, et al.
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DHA but Not EPA Emulsions Preserve Neurological and Mitochondrial Function after Brain Hypoxia-Ischemia in Neonatal Mice.
Dahkki: Korapat Mayurasakorn, et al.
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Exogenous 10 kDa-Heat Shock Protein Preserves Mitochondrial Function After Hypoxia/Reoxygenation
Dahkki: Leonardo Maciel, et al.
Almmustuhtton: (2020-05-01)

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.
Dahkki: Sowter, H, et al.
Almmustuhtton: (2003)

Regulation of angiogenesis by hypoxia: role of the HIF system.
Dahkki: Pugh, C, et al.
Almmustuhtton: (2003)

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Dahkki: Stolze, I, et al.
Almmustuhtton: (2004)

Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain.
Dahkki: Piotr Bednarczyk, et al.
Almmustuhtton: (2013-01-01)

Hypoxia-Induced Mitochondrial ROS and Function in Pulmonary Arterial Endothelial Cells
Dahkki: Harrison Wang, et al.
Almmustuhtton: (2024-11-01)

Oxygen sensing and hypoxia-induced responses.
Dahkki: Coleman, M, et al.
Almmustuhtton: (2007)

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
Dahkki: Appelhoff, R, et al.
Almmustuhtton: (2004)

Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.
Dahkki: Lakhal, S, et al.
Almmustuhtton: (2011)

Correction: PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function
Dahkki: Lijie Dong, et al.
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Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
Dahkki: Nathan P. Ward, et al.
Almmustuhtton: (2024-05-01)

Pan-genomic binding of hypoxia-inducible transcription factors.
Dahkki: Schödel, J, et al.
Almmustuhtton: (2013)

Pathological features of mitochondrial respiratory chain dysfunction
Dahkki: Chen, Walter W
Almmustuhtton: (2016)

The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor alpha.
Dahkki: Willam, C, et al.
Almmustuhtton: (2004)

Hypoxia and hypoxia-inducible factors in leukaemias
Dahkki: Margaux eDeynoux, et al.
Almmustuhtton: (2016-02-01)

Role of hypoxia-inducible factor-1 (HIF-1) is angiogenesis and tumour biology
Dahkki: Ratcliffe, P
Almmustuhtton: (1999)

Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice.
Dahkki: Ratcliffe, P, et al.
Almmustuhtton: (2016)

Functional hypoxia reduces mitochondrial calcium uptake
Dahkki: Chris Donnelly, et al.
Almmustuhtton: (2024-05-01)

Hypoxic regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements.
Dahkki: Firth, J, et al.
Almmustuhtton: (1995)