Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.

Hypoxia-inducible factor (HIF) mediates a large number of transcriptional responses to hypoxia and has an important role in processes that include angiogenesis and erythropoiesis. The HIF DNA binding complex consists of 2 basic-helix-loop-helix PAS proteins designated alpha and beta subunits. Regula...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Vaux, E, Metzen, E, Yeates, K, Ratcliffe, P
Format:	Journal article
Sprog:	English
Udgivet:	2001

Lignende værker

Mitochondrial respiratory function induces endogenous hypoxia.
af: Sara Prior, et al.
Udgivet: (2014-01-01)

The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia
af: Robert B. Hamanaka, et al.
Udgivet: (2016-04-01)

Nitrite protects mitochondrial structure and function under hypoxia
af: Ratcliffe, R, et al.
Udgivet: (2016)

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.
af: Masson, N, et al.
Udgivet: (2001)

From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
af: Ratcliffe, P
Udgivet: (2002)

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
af: Maxwell, P, et al.
Udgivet: (1999)

The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9.
af: Ulf Brockmeier, et al.
Udgivet: (2011-04-01)

Mitochondrial respiratory chain protein co-regulation in the human brain
af: Caroline Trumpff, et al.
Udgivet: (2022-05-01)

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression.
af: Wood, S, et al.
Udgivet: (1998)

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences.
af: Ebert, B, et al.
Udgivet: (1995)

Hypoxia and the regulation of gene expression.
af: Gleadle, J, et al.
Udgivet: (1998)

Mitochondrial metabolism regulation and epigenetics in hypoxia
af: Madison Laird, et al.
Udgivet: (2024-06-01)

The human side of hypoxia-inducible factor.
af: Smith, T, et al.
Udgivet: (2008)

Blood-based mitochondrial respiratory chain function in major depression
af: Johan Fernström, et al.
Udgivet: (2021-11-01)

Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression.
af: Ratcliffe, P, et al.
Udgivet: (1998)

Mammalian oxygen sensing and hypoxia inducible factor-1
af: Wood, S, et al.
Udgivet: (1997)

Hypoxia-induced mitochondrial stress granules
af: Chun-Ling Sun, et al.
Udgivet: (2023-07-01)

HIF hydroxylation and cellular oxygen sensing.
af: Metzen, E, et al.
Udgivet: (2004)

PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function
af: Lijie Dong, et al.
Udgivet: (2021-02-01)

DHA but Not EPA Emulsions Preserve Neurological and Mitochondrial Function after Brain Hypoxia-Ischemia in Neonatal Mice.
af: Korapat Mayurasakorn, et al.
Udgivet: (2016-01-01)

Exogenous 10 kDa-Heat Shock Protein Preserves Mitochondrial Function After Hypoxia/Reoxygenation
af: Leonardo Maciel, et al.
Udgivet: (2020-05-01)

Hypoxia and hypoxia-inducible factor signals regulate the development, metabolism, and function of B cells
af: Jinwei Zhang, et al.
Udgivet: (2022-08-01)

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.
af: Sowter, H, et al.
Udgivet: (2003)

Regulation of angiogenesis by hypoxia: role of the HIF system.
af: Pugh, C, et al.
Udgivet: (2003)

Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain.
af: Piotr Bednarczyk, et al.
Udgivet: (2013-01-01)

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
af: Stolze, I, et al.
Udgivet: (2004)

Hypoxia-Induced Mitochondrial ROS and Function in Pulmonary Arterial Endothelial Cells
af: Harrison Wang, et al.
Udgivet: (2024-11-01)

Oxygen sensing and hypoxia-induced responses.
af: Coleman, M, et al.
Udgivet: (2007)

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
af: Appelhoff, R, et al.
Udgivet: (2004)

Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.
af: Lakhal, S, et al.
Udgivet: (2011)

Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
af: Nathan P. Ward, et al.
Udgivet: (2024-05-01)

Correction: PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function
af: Lijie Dong, et al.
Udgivet: (2023-07-01)

Pathological features of mitochondrial respiratory chain dysfunction
af: Chen, Walter W
Udgivet: (2016)

Pan-genomic binding of hypoxia-inducible transcription factors.
af: Schödel, J, et al.
Udgivet: (2013)

The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor alpha.
af: Willam, C, et al.
Udgivet: (2004)

Role of hypoxia-inducible factor-1 (HIF-1) is angiogenesis and tumour biology
af: Ratcliffe, P
Udgivet: (1999)

Hypoxia and hypoxia-inducible factors in leukaemias
af: Margaux eDeynoux, et al.
Udgivet: (2016-02-01)

Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice.
af: Ratcliffe, P, et al.
Udgivet: (2016)

Functional hypoxia reduces mitochondrial calcium uptake
af: Chris Donnelly, et al.
Udgivet: (2024-05-01)

Hypoxic regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements.
af: Firth, J, et al.
Udgivet: (1995)