A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus.
Murine cytomegalovirus (MCMV) is an important animal model of human cytomegalovirus (HCMV), a (Beta)-Herpesvirus that infects the majority of the world's population and causes disease in neonates and immunocompromised adults. CD8(+) T cells are a major part of the immune response to MCMV and HC...
Main Authors: | Hutchinson, S, Sims, S, O'Hara, G, Silk, J, Gileadi, U, Cerundolo, V, Klenerman, P |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2011
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