Improved temporal resolution and linked hidden Markov modeling for switchable single-molecule FRET.

Improved temporal resolution and linked hidden Markov modeling for switchable single-molecule FRET.

Switchable FRET is the combination of single-molecule Förster resonance energy transfer (smFRET) with photoswitching, the reversible activation and deactivation of fluorophores by light. By photoswitching, multiple donor-acceptor fluorophore pairs can be probed sequentially, thus allowing observatio...

Bibliografske podrobnosti
Main Authors:	Uphoff, S, Gryte, K, Evans, G, Kapanidis, A
Format:	Journal article
Jezik:	English
Izdano:	2011

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