DNMT1 is predictive of survival and associated with Ki-67 expression in R-CHOP-treated diffuse large B-cell lymphomas

DNMT1 is a target of approved anti-cancer drugs including decitabine. However, the prognostic value of DNMT1 protein expression in R-CHOP-treated diffuse large B-cell lymphomas (DLBCLs) remains unexplored. Here we showed that DNMT1 was expressed in the majority of DLBCL cases (n = 209/230, 90.9%) wi...

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Main Authors: Loo, SK, Ch'ng, ES, Lawrie, CH, Muruzabal, MA, Gaafar, A, Pomposo, MP, Husin, A, Salleh, MS, Banham, AH, Pedersen, LM, Møller, MB, Green, TM, Wong, KK
格式: Journal article
出版: Elsevier 2017