NFKBIZ polymorphisms and susceptibility to pneumococcal disease in European and African populations.

NFKBIZ polymorphisms and susceptibility to pneumococcal disease in European and African populations.

The proinflammatory transcription factor nuclear factor-kappaB (NF-kappaB) has a central role in host defence against pneumococcal disease. Both rare mutations and common polymorphisms in the NFKBIA gene encoding the NF-kappaB inhibitor, IkappaB-alpha, associate with susceptibility to bacterial dise...

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Bibliographic Details
Main Authors:	Chapman, S, Khor, C, Vannberg, F, Rautanen, A, Segal, S, Moore, C, Davies, R, Day, N, Peshu, N, Crook, D, Berkley, J, Williams, T, Scott, J, Hill, A
Format:	Journal article
Language:	English
Published:	2010

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