Efficacy of B-type natriuretic peptide is coupled to phosphodiesterase 2A in cardiac sympathetic neurons

Elevated B-type natriuretic peptide (BNP) regulates cGMP-phosphodiesterase activity. Its elevation is regarded as an early compensatory response to cardiac failure where it can facilitate sympathovagal balance and cardiorenal homeostasis. However, recent reports suggest a paradoxical proadrenergic a...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Li, D, Lu, C, Hao, G, Wright, H, Woodward, L, Liu, K, Vergari, E, Surdo, N, Herring, N, Zaccolo, M, Paterson, D
Format: Journal article
Sprache:English
Veröffentlicht: American Heart Association 2015