An antigen processing polymorphism revealed by HLA-B8-restricted cytotoxic T lymphocytes which does not correlate with TAP gene polymorphism.

In previous studies of antigen presentation through HLA-B27, we identified a healthy person whose lymphoblastoid cells do not present three B27-restricted viral epitopes to specific cytotoxic T lymphocytes (CTL), despite adequate cell surface expression of HLA-B2702 of normal sequence. Similar findi...

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Bibliographic Details
Main Authors: Rowland-Jones, S, Powis, S, Sutton, J, Mockridge, I, Gotch, F, Murray, N, Hill, AB, Rosenberg, WM, Trowsdale, J, Mcmichael, A
Format: Journal article
Language:English
Published: 1993