Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

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Co-receptors add complexity to cell-cell signaling systems. The secreted semaphorin 3s (Sema3s) require a co-receptor, neuropilin (Nrp), to signal through plexin As (PlxnAs) in functions ranging from axon guidance to bone homeostasis, but the role of the co-receptor is obscure. Here we present the l...

Bibliografski detalji
Glavni autori:	Janssen, B, Malinauskas, T, Weir, G, Cader, M, Siebold, C, Jones, E
Format:	Journal article
Izdano:	2012

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