Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety
A series of 3-methylidene-1H-indol-2(3H)-ones substituted with a 5- or 6-pentafluorosulfanyl group has been synthesized by a Knoevenagel condensation reaction of SF5-substituted oxindoles with a range of aldehydes. The resulting products were characterized by X-ray crystallography studies and were t...
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Dades bibliogràfiques
Autors principals: |
Sansook, S,
Ocasio, CA,
Day, IJ,
Tizzard, GJ,
Coles, SJ,
Fedorov, O,
Bennett, JM,
Elkins, JM,
Spencer, J |
Format: | Journal article
|
Idioma: | English |
Publicat: |
Royal Society of Chemistry
2017
|