A simple method for the evaluation of receptor binding capacity of modified cytokines.
We have developed a flow cytometric method to evaluate the binding of interleukin-2 analogues to receptors. The method relies on competition for binding between a fluorescein-conjugated monoclonal antibody (MoAb) directed against the human interleukin-2 receptor alpha chain (fluorescein isothiocyana...
Main Authors: | Chianelli, M, Signore, A, Hicks, R, Testi, R, Negri, M, Beverley, P |
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Format: | Journal article |
Language: | English |
Published: |
1993
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