Variation in the immune response to adenoviral vectors in the brain: influence of mouse strain, environmental conditions and priming.

E1-deleted adenoviral vectors expressing the bacterial beta-galactosidase gene were inoculated into the brain of unprimed and primed C3H.He or C57BL/6J mice housed under either conventional or specific-pathogen-free (SPF) conditions. The kinetics of immune responses to both the vector and the transg...

Descrizione completa

Dettagli Bibliografici
Autori principali: Ohmoto, Y, Wood, M, Charlton, H, Kajiwara, K, Perry, V, Wood, K
Natura: Journal article
Lingua:English
Pubblicazione: 1999