Variation in the immune response to adenoviral vectors in the brain: influence of mouse strain, environmental conditions and priming.

E1-deleted adenoviral vectors expressing the bacterial beta-galactosidase gene were inoculated into the brain of unprimed and primed C3H.He or C57BL/6J mice housed under either conventional or specific-pathogen-free (SPF) conditions. The kinetics of immune responses to both the vector and the transg...

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Hlavní autoři: Ohmoto, Y, Wood, M, Charlton, H, Kajiwara, K, Perry, V, Wood, K
Médium: Journal article
Jazyk:English
Vydáno: 1999