Health and development of children born after assisted reproductive technology and sub-fertility compared to naturally conceived children: data from a national study.

In a non-matched case-control study using data from two large national cohort studies, we investigated whether indicators of child health and development up to 7 years of age differ between children conceived using assisted reproductive technology (ART), children born after sub-fertility (more than...

Full description

Bibliographic Details
Main Authors: Sutcliffe, A, Melhuish, E, Barnes, J, Gardiner, J
Format: Journal article
Language:English
Published: PAGEPress 2014
_version_ 1797104259260481536
author Sutcliffe, A
Melhuish, E
Barnes, J
Gardiner, J
author_facet Sutcliffe, A
Melhuish, E
Barnes, J
Gardiner, J
author_sort Sutcliffe, A
collection OXFORD
description In a non-matched case-control study using data from two large national cohort studies, we investigated whether indicators of child health and development up to 7 years of age differ between children conceived using assisted reproductive technology (ART), children born after sub-fertility (more than 24 months of trying for conception) and other children. Information on ART use/sub-fertility was available for 23,649 children. There were 227 cases (children conceived through ART) and two control groups: 783 children born to sub-fertile couples, and 22,639 children born to couples with no fertility issues. In models adjusted for social and demographic factors there were significant differences between groups in rate of hospital admissions before the children were 9 months old (P=0.029), with the ART group showing higher rates of hospital admission than the no fertility issues control group, the sub-fertile control group being intermediate between the two. Children born after ART had comparable health and development beyond 9 months of age to their naturally conceived peers. This applied to the whole sample and to a sub-sample of children from deprived neighborhoods.
first_indexed 2024-03-07T06:31:24Z
format Journal article
id oxford-uuid:f61a508f-be14-4c38-9d35-652d47ff99dc
institution University of Oxford
language English
last_indexed 2024-03-07T06:31:24Z
publishDate 2014
publisher PAGEPress
record_format dspace
spelling oxford-uuid:f61a508f-be14-4c38-9d35-652d47ff99dc2022-03-27T12:32:29ZHealth and development of children born after assisted reproductive technology and sub-fertility compared to naturally conceived children: data from a national study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f61a508f-be14-4c38-9d35-652d47ff99dcEnglishSymplectic Elements at OxfordPAGEPress2014Sutcliffe, AMelhuish, EBarnes, JGardiner, JIn a non-matched case-control study using data from two large national cohort studies, we investigated whether indicators of child health and development up to 7 years of age differ between children conceived using assisted reproductive technology (ART), children born after sub-fertility (more than 24 months of trying for conception) and other children. Information on ART use/sub-fertility was available for 23,649 children. There were 227 cases (children conceived through ART) and two control groups: 783 children born to sub-fertile couples, and 22,639 children born to couples with no fertility issues. In models adjusted for social and demographic factors there were significant differences between groups in rate of hospital admissions before the children were 9 months old (P=0.029), with the ART group showing higher rates of hospital admission than the no fertility issues control group, the sub-fertile control group being intermediate between the two. Children born after ART had comparable health and development beyond 9 months of age to their naturally conceived peers. This applied to the whole sample and to a sub-sample of children from deprived neighborhoods.
spellingShingle Sutcliffe, A
Melhuish, E
Barnes, J
Gardiner, J
Health and development of children born after assisted reproductive technology and sub-fertility compared to naturally conceived children: data from a national study.
title Health and development of children born after assisted reproductive technology and sub-fertility compared to naturally conceived children: data from a national study.
title_full Health and development of children born after assisted reproductive technology and sub-fertility compared to naturally conceived children: data from a national study.
title_fullStr Health and development of children born after assisted reproductive technology and sub-fertility compared to naturally conceived children: data from a national study.
title_full_unstemmed Health and development of children born after assisted reproductive technology and sub-fertility compared to naturally conceived children: data from a national study.
title_short Health and development of children born after assisted reproductive technology and sub-fertility compared to naturally conceived children: data from a national study.
title_sort health and development of children born after assisted reproductive technology and sub fertility compared to naturally conceived children data from a national study
work_keys_str_mv AT sutcliffea healthanddevelopmentofchildrenbornafterassistedreproductivetechnologyandsubfertilitycomparedtonaturallyconceivedchildrendatafromanationalstudy
AT melhuishe healthanddevelopmentofchildrenbornafterassistedreproductivetechnologyandsubfertilitycomparedtonaturallyconceivedchildrendatafromanationalstudy
AT barnesj healthanddevelopmentofchildrenbornafterassistedreproductivetechnologyandsubfertilitycomparedtonaturallyconceivedchildrendatafromanationalstudy
AT gardinerj healthanddevelopmentofchildrenbornafterassistedreproductivetechnologyandsubfertilitycomparedtonaturallyconceivedchildrendatafromanationalstudy